Dr. Molishree U. Joshi
Dr. Molishree Joshi is the manager of the Facility.
She received her Ph.D. from East Carolina University, where her graduate work focused on understanding the mechanism by which vascular endothelial cells and endothelial progenitors localize to developing tumors. To understand this process, she developed a real time-based protocol to objectively quantitate the adoptively transferred cells biolocalized to primary and metastatic tumors and other organs. Dr. Joshi's thesis work titled “The role of SDF-1α as a vasculogenic chemokine and endothelium-associated cell adhesion molecule for the recruitment of bone marrow-derived progenitor cells to developing tumors” provides data supporting the hypothesis that biolocalization of bone marrow-derived circulating endothelial progenitor cells to tumors is mediated by stromal derived factor (SDF-1α).
Subsequently, during her post-doctoral training, she applied herself to understanding the role of vitamin D in chemoprevention of prostate cancer. During this training she designed, cloned and/or used Functional Genomics tools like shRNA and ORF clone for gene expression modulation.
As the Managing Scientist of the Functional Genomics Facility, Dr. Joshi plans to use her versatile experience to guide and troubleshoot Functional Genomics experiments across biomedical disciplines. Her goal is to expand the current repertoire of Functional Genomics knowledge and tools across campuses in Colorado.
She looks forward to providing excellent customer service and scientific support.